Severe Acute Generalized Exanthematous Pustulosis Induced by Hydroxychloroquine Mimicking Toxic Epidermal Necrolysis
نویسندگان
چکیده
Anti-malarial drugs may induce numerous cutaneous adverse drug reactions as well as exacerbation of psoriasis. Acute generalized exanthematous pustulosis (AGEP) is a clinical reaction pattern that is principally drug induced and is characterized by acute, extensive formation of non-follicular sterile pustules on an erythematous and oedematous substrate. Hydroxychloroquine (HCQ), an anti-malarial drug widely used to treat rheumatic and dermatologic diseases, has been described as an uncommon cause of AGEP. We report a 45-year-old woman who developed severe bullous AGEP mimicking toxic epidermal necrolysis after the intake of HCQ.
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